Darrick T Balu Selected Research

Serine (L-Serine)

1/2022	Inhibition of glial D-serine release rescues synaptic damage after brain injury.
1/2020	D-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders.
10/2019	Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease.
1/2018	Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning.
1/2018	DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia.
1/2018	Astrocytes in primary cultures express serine racemase, synthesize d-serine and acquire A1 reactive astrocyte features.
1/2018	The Role of Serine Racemase in the Pathophysiology of Brain Disorders.
8/2017	Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury.
3/2016	History of the Concept of Disconnectivity in Schizophrenia.
2/2015	The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond.

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Darrick T Balu Research Topics

Disease

18	Schizophrenia (Dementia Praecox) 01/2021 - 05/2008
4	Cognitive Dysfunction 01/2021 - 02/2015
3	AIDS-Related Complex (ARC) 01/2018 - 09/2014
2	Brain Injuries (Brain Injury) 01/2022 - 08/2017
2	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022 - 08/2017
2	Psychotic Disorders (Schizoaffective Disorder) 01/2021 - 01/2018
2	Alzheimer Disease (Alzheimer's Disease) 10/2019 - 10/2018
1	Anxiety Disorders (Anxiety Disorder) 01/2020
1	Disease Progression 10/2019
1	Amyloid Plaque 10/2019
1	Bipolar Disorder (Manic Depressive Psychosis) 11/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2018
1	Brain Diseases (Brain Disorder) 01/2018
1	Atrophy 01/2018
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2018
1	Mental Disorders (Mental Disorder) 02/2015
1	Hyperglycemia 02/2012
1	Nervous System Diseases (Neurological Disorders) 02/2012

Drug/Important Bio-Agent (IBA)

12	Serine (L-Serine)FDA Link 01/2022 - 06/2013
10	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 01/2011
5	serine racemaseIBA 10/2019 - 06/2013
4	Proteins (Proteins, Gene)FDA Link 11/2018 - 09/2014
4	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2018 - 05/2012
3	DysbindinIBA 01/2019 - 01/2011
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018 - 05/2008
2	Phosphotransferases (Kinase)IBA 10/2018 - 03/2015
2	Messenger RNA (mRNA)IBA 01/2018 - 02/2012
2	D-Aspartic Acid (D Aspartate)IBA 01/2018 - 03/2016
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Amyloid (Amyloid Fibrils)IBA 10/2019
1	EnzymesIBA 10/2019
1	CaspasesIBA 10/2018
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 10/2018
1	MicroRNAs (MicroRNA)IBA 10/2018
1	Neuroprotective AgentsIBA 10/2018
1	AcetyltransferasesIBA 10/2018
1	Peptide Hydrolases (Proteases)FDA Link 10/2018
1	CalpainIBA 10/2018
1	ChromatinIBA 01/2018
1	CalciumIBA 01/2018
1	ParvalbuminsIBA 01/2018
1	Glutamate Receptors (Glutamate Receptor)IBA 03/2016
1	Metabotropic Glutamate 5 ReceptorIBA 01/2016
1	TropomyosinIBA 03/2015
1	Dizocilpine Maleate (Dizocilpine)IBA 03/2015
1	trkB ReceptorIBA 03/2015
1	Biological ProductsIBA 02/2015
1	Serotonin (5 Hydroxytryptamine)IBA 02/2014
1	Glutamic Acid (Glutamate)FDA Link 02/2014
1	Antipsychotic Agents (Antipsychotics)IBA 02/2014
1	Insulin (Novolin)FDA Link 02/2012
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 02/2012
1	CorticosteroneIBA 02/2012
1	Protein Isoforms (Isoforms)IBA 02/2012
1	DNA (Deoxyribonucleic Acid)IBA 02/2012
1	NeuregulinsIBA 01/2011
1	Antidepressive Agents (Antidepressants)IBA 05/2008